Description bibliographique disponible à l'adresse http://www.loc.gov/catdir/enhancements/fy0739/2007017891-d.html

Notes bibliogr. Index

P. 1 The role of medicinal chemistry in drug discovery / John A. Lowe III P. 11 Process research: how much? how soon? / Neal G. Anderson P. 31 Aromatase inhibitors for breast cancer : exemestane (Aromasin), anastrozole (Arimidex), and letrozole (Femara) / Jie Jack Li P. 39 Quinolone antibiotics : levofloxacin (Levaquin), moxifloxacin (Avelox), gemifloxacin (Factive), and garenoxacin (T-3811) / Chris Limberakis P. 71 Triazole antifungals : itraconazole (Sporanox), fluconazole (Diflucan), voriconazole (Vfend), and fosfluconazole (Prodif) / Andrew S. Bell P. 83 Non-nucleoside HIV reverse transcriptase inhibitors / Arthur Harms P. 95 Neuraminidase inhibitors for influenza : oseltamivir phosphate (Tamiflu) and zanamivir (Relenza) / Douglas S. Johnson and Jie Jack Li P. 117 Peroxisome proliferator-activated receptor (PPAR) agonists for type 2 diabetes / Jin Li P. 129 Angiotensin AT1 antagonists for hypertension / Larry Yet P. 143 Leading ACE inhibitors for hypertension / Victor J. Cee and Edward J. Olhava P. 159 Dihydropyridine calcium channel blockers for hypertension / Daniel P. Christen P. 169 Second-generation HMG-CoA reductase inhibitors / Jeffrey A. Pfefferkorn P. 183 Cholesterol absorption inhibitors: ezetimibe (zetia) / Stuart B. Rosenblum P. 199 Dual selective serotonin and norepinephrine reuptake inhibitors (SSNRIs) for depression / Marta Piñeiro-Núñez P. 215 GABA receptor agonists for insomnia : zolpidem (Ambien), zaleplon (Sonata), eszopiclone (Estorra, Lunesta), and indiplon / Peter R. Guzzo P. 225 Ligands: neurontin (Gabapentin) and lyrica (Pregabalin) / Po-Wai Yuen P. 241 Approved treatments for attention deficit hyperactivity disorder : amphetamine (Adderall), methylphenidate (Ritalin), and atomoxetine (Straterra) / David L. Gray