000			04496clm0a2200493 4500
001			7433
009			149041004
003			http://www.sudoc.fr/149041004
005			20250630091754.0
010			_a9780387764979
017	7	0	_a10.1007/978-0-387-76497-9 _2DOI
090			_a7433
099			_tOUVR _zALEX19717
100			_a20110106f20 u y0frey50 ba
101	0		_aeng _2639-2
102			_aUS
105			_ay |||||||||
135			_adr|||||||||||
181			_6z01 _ctxt _2rdacontent
181		1	_6z01 _ai# _bxxxe##
182			_6z01 _cc _2rdamedia
182		1	_6z01 _ab
183		1	_6z01 _aceb _2RDAfrCarrier
200	1		_aHandbook of Single-Molecule Biophysics _fedited by Peter Hinterdorfer, Antoine Oijen
214		0	_aNew York, NY _cSpringer New York
214		2	_aCham _cSpringer Nature _d[20..]
327	1		_aSingle-Molecule Fluorescent Particle Tracking _aSingle-Molecule Analysis of Biomembranes _aSingle-Molecule Imaging in Live Cells _aFluorescence Imaging at Sub-Diffraction-Limit Resolution with Stochastic Optical Reconstruction Microscopy _aSingle-Molecule FRET: Methods and Biological Applications _aSingle-Molecule Enzymology _aSingle-Molecule Studies of Rotary Molecular Motors _aFluorescence Correlation Spectroscopy in Living Cells _aPrecise Measurements of Diffusion in Solution by Fluorescence Correlations Spectroscopy _aSingle-Molecule Studies of Nucleic Acid Interactions Using Nanopores _aNanopores: Generation, Engineering, and Single-Molecule Applications _aSingle-Molecule Manipulation Using Optical Traps _aMagnetic Tweezers for Single-Molecule Experiments _aFolding of Proteins under Mechanical Force _aProbing the Energy Landscape of Protein-Binding Reactions by Dynamic Force Spectroscopy _aProbing Single Membrane Proteins by Atomic Force Microscopy _aHigh-Speed Atomic Force Microscopy _aRecognition Imaging Using Atomic Force Microscopy _aAtomic Force Microscopy of Protein–Protein Interactions _aA New Approach to Analysis of Single-Molecule Force Measurements _aSingle-Molecule Recognition: Extracting Information from Individual Binding Events and Their Correlation
330			_aThe last decade has seen the development of a number of novel biophysical methods that allow the manipulation and study of individual biomolecules. The ability to monitor biological processes at this fundamental level of sensitivity has given rise to an improved understanding of the underlying molecular mechanisms. Through the removal of ensemble averaging, distributions and fluctuations of molecular properties can be characterized, transient intermediates identified, and catalytic mechanisms elucidated. By applying forces on biomolecules while monitoring their activity, important information can be obtained on how proteins couple function to structure. The Handbook of Single-Molecule Biophysics provides an introduction to these techniques and presents an extensive discussion of the new biological insights obtained from them. Coverage includes: Experimental techniques to monitor and manipulate individual biomolecules The use of single-molecule techniques in super-resolution and functional imaging Single-molecule studies of physical properties of biomolecules Single-molecule enzymology and biochemistry Single molecules in the membrane Single-molecule techniques in living cells Integration of single-molecule biophysics and nanoscience
371	0		_aAccès en ligne pour les établissements français bénéficiaires des licences nationales
371	0		_aAccès soumis à abonnement pour tout autre établissement
371	1		_aConditions particulières de réutilisation pour les bénéficiaires des licences nationales _chttps://www.licencesnationales.fr/springer-nature-ebooks-contrat-licence-ln-2017
452			_0138021406 _tHandbook of single-molecule biophysics _fPeter Hinterdorfer, Antoine van Oijen editors _cNew York _nSpringer _dcop. 2009 _p1 vol. (xxi-626 p.)
606			_aPhysics _2lc
606			_aNanotechnology _2lc
606			_aMedicine _2lc
606			_aBiomedical engineering _2lc
606			_aLife sciences. _2lc
615			_a@Physics and Astronomy _n11651 _2Springer
676			_a571.4 _v23
680			_aQH505
702		1	_3138021619 _aHinterdorfer _bPeter _4651
702		1	_3138021813 _aOijen _bAntoine van _4651
856	4		_qPDF _uhttps://doi.org/10.1007/978-0-387-76497-9 _zAccès sur la plateforme de l'éditeur
856	4		_uhttps://revue-sommaire.istex.fr/ark:/67375/8Q1-CHCMP1HR-0 _zAccès sur la plateforme Istex